In vitro complex formation of human PYRIN domain-only protein 3 prevented by self-oligomerization of ASC PYD domain

In vitro complex formation of human PYRIN domain-only protein 3 prevented by self-oligomerization of ASC PYD domain

The formation of inflammasome complexes contributes inactivation of inflammatory caspases viz caspase 1, which is generally considered essential for the innate response. Three proteins constituted this inflammasome complex, such as Nod-like receptors (NLRP or AIM2), ASC possessing caspase-recruiting...

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Bibliographic Details
Main Authors: Eijaz Ahmed Bhat, Nasreena Sajjad, Javeed Ahmad Tantray, Yan-Yan Hor, Irfan A. Rather
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Saudi Journal of Biological Sciences
Subjects:
Innate immunity
POP3
ASC
Inflammasome
PYD domain
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X20307130

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http://www.sciencedirect.com/science/article/pii/S1319562X20307130

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