L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism

L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism

Abstract 18F-FDG PET/CT has been used as an indicator of chemotherapy effects, but cancer cells can remain even when no FDG uptake is detected, indicating the importance of exploring other metabolomic pathways. Therefore, we explored the amino acid metabolism, including L-type amino acid transporter...

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Main Authors: Miku Sato, Narumi Harada-Shoji, Takafumi Toyohara, Tomoyoshi Soga, Masatoshi Itoh, Minoru Miyashita, Hiroshi Tada, Masakazu Amari, Naohiko Anzai, Shozo Furumoto, Takaaki Abe, Takashi Suzuki, Takanori Ishida, Hironobu Sasano
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80668-5

Internet

https://doi.org/10.1038/s41598-020-80668-5

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