Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway

Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway

Viperid snakebite envenomation is characterized by inflammatory events including increase in vascular permeability. A copious exudate is generated in tissue injected with venom, whose proteomics analysis has provided insights into the mechanisms of venom-induced tissue damage. Hereby it is reported...

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Bibliographic Details
Main Authors: Alexandra Rucavado, Carolina A. Nicolau, Teresa Escalante, Junho Kim, Cristina Herrera, José María Gutiérrez, Jay W. Fox
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Toxins
Subjects:
snake venom metalloproteinases (SVMPs)
TLR4
damage associated molecular pattern molecules (DAMPs)
exudate
increased vascular permeability
Online Access:http://www.mdpi.com/2072-6651/8/12/349

Internet

http://www.mdpi.com/2072-6651/8/12/349

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