Paradoxical function of orexin/hypocretin circuits in a mouse model of Huntington's disease
Huntington's disease (HD) is a neurodegenerative disorder involving progressive motor disturbances, cognitive decline, and desynchronized sleep–wake rhythms. Recent studies revealed that restoring normal sleep–wake cycles can improve cognitive function in HD mice, suggesting that some sleep/wak...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-06-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S096999611100060X |