Understanding heterogeneous tumor microenvironment in metastatic melanoma.

Understanding heterogeneous tumor microenvironment in metastatic melanoma.

A systemic analysis of the tumor-immune interactions within the heterogeneous tumor microenvironment is of particular importance for understanding the antitumor immune response. We used multiplexed immunofluorescence to elucidate cellular spatial interactions and T-cell infiltrations in metastatic m...

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Bibliographic Details
Main Authors: Yiyi Yan, Alexey A Leontovich, Michael J Gerdes, Keyur Desai, Jinhong Dong, Anup Sood, Alberto Santamaria-Pang, Aaron S Mansfield, Chrystal Chadwick, Rong Zhang, Wendy K Nevala, Thomas J Flotte, Fiona Ginty, Svetomir N Markovic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216485

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https://doi.org/10.1371/journal.pone.0216485

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