Insight into Neutrophil Extracellular Traps through Systematic Evaluation of Citrullination and Peptidylarginine Deiminases

In rheumatoid arthritis, an autoimmune inflammatory arthritis, citrullinated proteins are targeted by autoantibodies and thus thought to drive disease. Neutrophil extracellular traps (NETs) are a source of citrullinated proteins and are increased in rheumatoid arthritis and therefore also implicated...

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Bibliographic Details
Main Authors: Caitlyn L. Holmes, Daeun Shim, John Kernien, Chad J. Johnson, Jeniel E. Nett, Miriam A. Shelef
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/2160192