A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.

Several diterpenoids isolated from terrestrial and marine environments have been identified as important anti-inflammatory agents. Although considerable progress has been made in the area of anti-inflammatory treatment, the search for more effective and safer compounds is a very active field of rese...

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Bibliographic Details
Main Authors: Yisett González, Deborah Doens, Ricardo Santamaría, Marla Ramos, Carlos M Restrepo, Luciana Barros de Arruda, Ricardo Lleonart, Marcelino Gutiérrez, Patricia L Fernández
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3865250?pdf=render