Structural Stability of ADTC5 Peptide: Conformational Insights into Dynamics and Its Binding Mode

The cyclic structure of ADTC5 (Ac-CDTPPVC-NH2) peptide is known has ability to modulate homo dimer E-cadherin interactions to form adherens junction at the intercellular junction.  The ability to inhibit E-cadherin interaction has become important to increase paracellular porosity in delivering drug...

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Bibliographic Details
Main Authors: Parsaoran Siahaan, Vivitri Dewi Prasasty, Bungaran David Simanjuntak, Suci Hildayani, Khairul Anam
Format: Article
Language:English
Published: University of Brawijaya 2017-06-01
Series:Journal of Tropical Life Science
Subjects:
Online Access:http://jtrolis.ub.ac.id/index.php/jtrolis/article/view/681