Emerging Effects of Sepantronium Bromide (YM155) on MOLT-4 Cell Line Apoptosis Induction and Expression of Critical Genes Involved in Apoptotic Pathways
Purpose: Sepantronium bromide (YM155) is a Survivin inhibitor which recently advanced as an anticancer agent in phase II clinical trials. Survivin belongs to IAP (inhibitor of apoptosis) gene family and is a pivotal target for treatment due to its overexpression and oncogenic function in many malign...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2020-01-01
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Series: | Advanced Pharmaceutical Bulletin |
Subjects: | |
Online Access: | https://apb.tbzmed.ac.ir/PDF/apb-27892 |