Bi-functionalization of a calcium phosphate-coated titanium surface with slow-release simvastatin and metronidazole to provide antibacterial activities and pro-osteodifferentiation capabilities.

Bi-functionalization of a calcium phosphate-coated titanium surface with slow-release simvastatin and metronidazole to provide antibacterial activities and pro-osteodifferentiation capabilities.

Coating the surface of titanium implants or other bone graft substitute materials with calcium phosphate (Ca-P) crystals is an effective way to enhance the osteoconduction of the implants. Ca-P coating alone cannot confer pro-osteodifferentiation and antibacterial capabilities on implants; however,...

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Bibliographic Details
Main Authors: Yunsong Liu, Xiao Zhang, Yang Liu, Xiaoxiao Jin, Cong Fan, Hongqiang Ye, Meng'en Ou, Longwei Lv, Gang Wu, Yongsheng Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4028224?pdf=render

Internet

http://europepmc.org/articles/PMC4028224?pdf=render

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