Towards a Central Role of <em>ISL1</em> in the Bladder Exstrophy–Epispadias Complex (BEEC): Computational Characterization of Genetic Variants and Structural Modelling

Genetic factors play a critical role in the development of human diseases. Recently, several molecular genetic studies have provided multiple lines of evidence for a critical role of genetic factors in the expression of human bladder exstrophy-epispadias complex (BEEC). At this point, <i>ISL1&...

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Bibliographic Details
Main Authors: Amit Sharma, Tikam Chand Dakal, Michael Ludwig, Holger Fröhlich, Riya Mathur, Heiko Reutter
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/9/12/609