Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models

Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models

Abstract Background Patient-derived tumor models are the new standard for pre-clinical drug testing and biomarker discovery. However, the emerging technology of primary pancreatic cancer organoids has not yet been broadly implemented in research, and complex organotypic models using organoids in co-...

Full description

Bibliographic Details
Main Authors: Susan Tsai, Laura McOlash, Katie Palen, Bryon Johnson, Christine Duris, Qiuhui Yang, Michael B. Dwinell, Bryan Hunt, Douglas B. Evans, Jill Gershan, Michael A. James
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Cancer
Subjects:
Pancreatic Cancer
PDAC
Organoid
Organotypic culture
Microenvironment
Tumor stroma
Online Access:http://link.springer.com/article/10.1186/s12885-018-4238-4

Internet

http://link.springer.com/article/10.1186/s12885-018-4238-4

Similar Items