A simple and robust vector-based shRNA expression system used for RNA interference.

A simple and robust vector-based shRNA expression system used for RNA interference.

BACKGROUND: RNA interference (RNAi) mediated by small interfering RNAs (siRNAs) or short hairpin RNAs (shRNAs) has become a powerful genetic tool for conducting functional studies. Previously, vector-based shRNA-expression strategies capable of inducing RNAi in viable cells have been developed, howe...

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Bibliographic Details
Main Authors: Xue-jun Wang, Ying Li, Hai Huang, Xiu-juan Zhang, Pei-wen Xie, Wei Hu, Dan-dan Li, Sheng-qi Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3566080?pdf=render

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http://europepmc.org/articles/PMC3566080?pdf=render

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