Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR) Regulation across Multiple Mouse Strains

Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR) Regulation across Multiple Mouse Strains

Calorie restriction (CR) has long been used to study lifespan effects and oppose the development of a broad array of age-related biological and pathological changes (increase healthspan). Yet, a comprehensive comparison of the metabolic phenotype across different genetic backgrounds to identify comm...

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Bibliographic Details
Main Authors: Sunil Kochhar, Tomas A. Prolla, Richard Weindruch, Laeticia Da Silva, Ivan Montoliu, Jamie L. Barger, François-Pierre J. Martin, Sebastiano Collino
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Metabolites
Subjects:
metabolomics
healthy ageing
calorie restriction
lipidomics
Online Access:http://www.mdpi.com/2218-1989/3/4/881

Internet

http://www.mdpi.com/2218-1989/3/4/881

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