Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments

Short cationic peptides and nucleotides can form complex coacervates, but the influence of reduced multivalency on coacervate functionality was not investigated. Here, the authors report that coacervates formed from short polyions generate distinct pH microenvironments, accumulate RNA and preserve n...

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Bibliographic Details
Main Authors: Fatma Pir Cakmak, Saehyun Choi, McCauley O. Meyer, Philip C. Bevilacqua, Christine D. Keating
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19775-w