Trichostatin a Promotes Cardiomyocyte Differentiation of Rat Mesenchymal Stem Cells after 5-Azacytidine Induction or during Coculture with Neonatal Cardiomyocytes via a Mechanism Independent of Histone Deacetylase Inhibition
This study was to investigate the effect of trichostatin A (TSA), a histone deacetylase (HDAC) inhibitor, on cardiac differentiation of bone marrow mesenchymal stem cells (MSCs) in vitro. Rat MSCs were isolated and divided into six groups: 1) control; 2) 5-azacytidine treatment (5-aza, 10 μM); 3) tr...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2012-05-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/096368911X593145 |