Association of Polymorphisms in C-Reactive Protein (CRP) Promoter -821 A>G, -390 C>A/T, and Plasma Interferon-α (IFN-α) with Plasma CRP Level in Javanese Systemic Lupus Erythematosus (SLE) Patients

Background: As an acute-phase reactant, CRP is needed to clear apoptotic cells and immune complexes in SLE. This unresponsive CRP may be caused by genetic variation and abundant IFN-α that might inhibit CRP secretion. This study aims to analyze the association of single nucleotide polymorphisms (SNP...

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Bibliographic Details
Main Authors: Awalia Awalia, Harianto Notopuro, Joewono Soeroso
Format: Article
Language:English
Published: Interna Publishing 2021-07-01
Series:Acta Medica Indonesiana
Subjects:
Online Access:http://actamedindones.org/index.php/ijim/article/view/1796