Current Pharmacological Strategies for Duchenne Muscular Dystrophy

Current Pharmacological Strategies for Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a lethal, X-linked neuromuscular disorder caused by the absence of dystrophin protein, which is essential for muscle fiber integrity. Loss of dystrophin protein leads to recurrent myofiber damage, chronic inflammation, progressive fibrosis, and dysfunction of mus...

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Bibliographic Details
Main Authors: Shanshan Yao, Zihao Chen, Yuanyuan Yu, Ning Zhang, Hewen Jiang, Ge Zhang, Zongkang Zhang, Baoting Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Duchenne muscular dystrophy
pharmacological therapeutics
skeletal muscle
fibrosis
inflammation
regeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.689533/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.689533/full

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