P2X7 Interactions and Signaling – Making Head or Tail of It

Extracellular adenine nucleotides play important roles in cell–cell communication and tissue homeostasis. High concentrations of extracellular ATP released by dying cells are sensed as a danger signal by the P2X7 receptor, a non-specific cation channel. Studies in P2X7 knockout mice and numerous dis...

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Bibliographic Details
Main Authors: Robin Kopp, Anna Krautloher, Antonio Ramírez-Fernández, Annette Nicke
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00183/full