Reversal of hyperglycemia by insulin-secreting rat bone marrow- and blastocyst-derived hypoblast stem cell-like cells.

Reversal of hyperglycemia by insulin-secreting rat bone marrow- and blastocyst-derived hypoblast stem cell-like cells.

β-cell replacement may efficiently cure type 1 diabetic (T1D) patients whose insulin-secreting β-cells have been selectively destroyed by autoantigen-reactive T cells. To generate insulin-secreting cells we used two cell sources: rat multipotent adult progenitor cells (rMAPC) and the highly similar...

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Main Authors: Anujith Kumar, Antonio Lo Nigro, Conny Gysemans, Qing Cai, Camila Esguerra, Molly Nelson-Holte, Yves Heremans, María Jiménez-González, Angelo Porciuncula, Chantal Mathieu, Bert Binas, Harry Heimberg, Felipe Prosper, Bernhard Hering, Catherine M Verfaillie, Miguel Barajas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3650069?pdf=render

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http://europepmc.org/articles/PMC3650069?pdf=render

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