Preferential amplification of CD8 effector-T cells after transcutaneous application of an inactivated influenza vaccine: a randomized phase I trial.

Preferential amplification of CD8 effector-T cells after transcutaneous application of an inactivated influenza vaccine: a randomized phase I trial.

Current conventional vaccination approaches do not induce potent CD8 T-cell responses for fighting mostly variable viral diseases such as influenza, avian influenza viruses or HIV. Following our recent study on vaccine penetration by targeting of vaccine to human hair follicular ducts surrounded by...

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Bibliographic Details
Main Authors: Behazine Combadière, Annika Vogt, Brice Mahé, Dominique Costagliola, Sabrina Hadam, Olivia Bonduelle, Wolfram Sterry, Shlomo Staszewski, Hans Schaefer, Sylvie van der Werf, Christine Katlama, Brigitte Autran, Ulrike Blume-Peytavi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2877091?pdf=render

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http://europepmc.org/articles/PMC2877091?pdf=render

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