Acetylcholine Delays Atrial Activation to Facilitate Atrial Fibrillation
BackgroundAcetylcholine (ACh) shortens action potential duration (APD) in human atria. APD shortening facilitates atrial fibrillation (AF) by reducing the wavelength for reentry. However, the influence of ACh on electrical conduction in human atria and its contribution to AF are unclear, particularl...
Main Authors: | Jason D. Bayer, Bastiaan J. Boukens, Sébastien P. J. Krul, Caroline H. Roney, Antoine H. G. Driessen, Wouter R. Berger, Nicoline W. E. van den Berg, Arie O. Verkerk, Edward J. Vigmond, Ruben Coronel, Joris R. de Groot |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-09-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphys.2019.01105/full |
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