Brain Microglial Activation in Chronic Pain-Associated Affective Disorder

A growing body of evidence from both clinical and animal studies indicates that chronic neuropathic pain is associated with comorbid affective disorders. Spinal cord microglial activation is involved in nerve injury-induced pain hypersensitivity characterizing neuropathic pain. However, there is a l...

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Bibliographic Details
Main Authors: Ellane Eda Barcelon, Woo-Hyun Cho, Sang Beom Jun, Sung Joong Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00213/full