The Multifaceted Role of Astrocyte Connexin 43 in Ischemic Stroke Through Forming Hemichannels and Gap Junctions

Ischemic stroke is a multi-factorial cerebrovascular disease with high worldwide morbidity and mortality. In the past few years, multiple studies have revealed the underlying mechanism of ischemia/reperfusion injury, including calcium overload, amino acid toxicity, oxidative stress, and inflammation...

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Bibliographic Details
Main Authors: Zhen Liang, Xu Wang, Yulei Hao, Lin Qiu, Yingyue Lou, Yaoting Zhang, Di Ma, Jiachun Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00703/full