Global analysis of the impact of environmental perturbation on cis-regulation of gene expression.

Global analysis of the impact of environmental perturbation on cis-regulation of gene expression.

Genetic variants altering cis-regulation of normal gene expression (cis-eQTLs) have been extensively mapped in human cells and tissues, but the extent by which controlled, environmental perturbation influences cis-eQTLs is unclear. We carried out large-scale induction experiments using primary human...

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Bibliographic Details
Main Authors: Elin Grundberg, Veronique Adoue, Tony Kwan, Bing Ge, Qing Ling Duan, Kevin C L Lam, Vonda Koka, Andreas Kindmark, Scott T Weiss, Kelan Tantisira, Hans Mallmin, Benjamin A Raby, Olle Nilsson, Tomi Pastinen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3024267?pdf=render

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http://europepmc.org/articles/PMC3024267?pdf=render

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