Repurposing Ziyuglycoside II Against Colorectal Cancer via Orchestrating Apoptosis and Autophagy

Effective chemotherapy drugs for colorectal cancer remain a challenge. In this research, Ziyuglycoside II (Ziyu II), exhibits considerable antitumor activity against CRC cells both in vitro and in vivo. The results showed that Ziyu II induced apoptosis through the accumulation of reactive oxygen spe...

Full description

Bibliographic Details
Main Authors: Can Bai, Zhe Zhang, Li Zhou, Huan-Yu Zhang, Yan Chen, Yong Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
Akt
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.576547/full