Flexible lab-tailored cut-offs for suitability of formalin-fixed tumor samples for diagnostic mutational analyses.

The selection of proper tissues from formalin-fixed and paraffin-embedded tumors before diagnostic molecular testing is responsibility of the pathologist and represents a crucial step to produce reliable test results. The international guidelines suggest two cut-offs, one for the percentage and one...

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Bibliographic Details
Main Authors: Sara Mariani, Cristiana Di Bello, Lisa Bonello, Fabrizio Tondat, Donatella Pacchioni, Luca Molinaro, Antonella Barreca, Luigia Macrì, Luigi Chiusa, Paola Francia di Celle, Paola Cassoni, Anna Sapino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4386759?pdf=render