Anti-inflammatory and -apoptotic effects of a long-term herbal extract treatment on DSS-induced colitis in mice fed with high AGEs-fat diet

Abstract Background Obesity is associated with many comorbidities including inflammatory bowel disease (IBD). We investigated prophylactic effects of an herbal extract (HE) on the DSS-induced colitis mice challenged with high AGEs-fat diet 60% (HFD). Methods Six-week-old C57BL/6 male mice were fed w...

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Main Authors: Fatemeh Azizian-Farsani, Marcin Osuchowski, Navid Abedpoor, Farzad Seyed Forootan, Maryam Derakhshan, Mohammad Hossein Nasr-Esfahani, Mohammad Hasan Sheikhha, Kamran Ghaedi
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Nutrition & Metabolism
Subjects:
Online Access:https://doi.org/10.1186/s12986-021-00603-x