Guanosine protects against Ca2+-induced mitochondrial dysfunction in rats

Guanosine protects against Ca2+-induced mitochondrial dysfunction in rats

Mitochondria play an important role in cell life and in the regulation of cell death. In addition, mitochondrial dysfunction contributes to a wide range of neuropathologies. The nucleoside Guanosine (GUO) is an endogenous molecule, presenting antioxidant properties, possibly due to its direct scaven...

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Bibliographic Details
Main Authors: Aline Alves Courtes, Nelson Rodrigues de Carvalho, Débora Farina Gonçalves, Diane Duarte Hartmann, Pamela Carvalho da Rosa, Fernando Dobrachinski, Jeferson Luis Franco, Diogo Onofre Gomes de Souza, Félix Alexandre Antunes Soares
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Nucleoside
Guanine-based purine
Calcium
High-resolution respirometry
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218387559

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http://www.sciencedirect.com/science/article/pii/S0753332218387559

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