Exploring the potential of deep-blue autofluorescence for monitoring amyloid fibril formation and dissociation

Protein aggregation into amyloid fibrils has been linked to multiple neurodegenerative disorders. Determining the kinetics of fibril formation, as well as their structural stability are important for the mechanistic understanding of amyloid aggregation. Tracking both fibril association and dissociat...

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Bibliographic Details
Main Authors: Mantas Ziaunys, Tomas Sneideris, Vytautas Smirnovas
Format: Article
Language:English
Published: PeerJ Inc. 2019-08-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/7554.pdf