Neurotrophin-induced migration and neuronal differentiation of multipotent astrocytic stem cells in vitro.

Hypoxic ischemic encephalopathy (HIE) affects 2-3 per 1000 full-term neonates. Up to 75% of newborns with severe HIE die or have severe neurological handicaps. Stem cell therapy offers the potential to replace HIE-damaged cells and enhances the autoregeneration process. Our laboratory implanted Mult...

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Bibliographic Details
Main Authors: Martha Douglas-Escobar, Candace Rossignol, Dennis Steindler, Tong Zheng, Michael D Weiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3520915?pdf=render