The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia

The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia

While cancer has been long recognized as a disease of the genome, the importance of epigenetic mechanisms in neoplasia was acknowledged more recently. The most active epigenetic marks are DNA methylation and histone protein modifications and they are involved in basic biological phenomena in every c...

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Bibliographic Details
Main Authors: Szymon Janczar, Karolina Janczar, Agata Pastorczak, Hani Harb, Adam J. W. Paige, Beata Zalewska-Szewczyk, Marian Danilewicz, Wojciech Mlynarski
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Cancers
Subjects:
acute lymphoblastic leukemia
B lymphocytes
histone modifications
chromatin modifiers
Online Access:http://www.mdpi.com/2072-6694/9/1/2

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http://www.mdpi.com/2072-6694/9/1/2

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