Improving the understanding of cytoneme-mediated morphogen gradients by in silico modeling.

Morphogen gradients are crucial for the development of organisms. The biochemical properties of many morphogens prevent their extracellular free diffusion, indicating the need of an active mechanism for transport. The involvement of filopodial structures (cytonemes) has been proposed for morphogen s...

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Bibliographic Details
Main Authors: Adrián Aguirre-Tamaral, Isabel Guerrero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009245