A Type III Effector NleF from EHEC Inhibits Epithelial Inflammatory Cell Death by Targeting Caspase-4

A Type III Effector NleF from EHEC Inhibits Epithelial Inflammatory Cell Death by Targeting Caspase-4

Enterohemorrhagic E. coli (EHEC) is a highly pathogenic bacterial strain capable of inducing severe gastrointestinal disease. Here, we show that EHEC uses the T3SS effector NleF to counteract the host inflammatory response by dampening caspase-4-mediated inflammatory epithelial cell death and by pre...

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Bibliographic Details
Main Authors: Ting Song, Kaiwu Li, Wei Zhou, Jing Zhou, Yuan Jin, Hongmei Dai, Tingting Xu, Mingda Hu, Hongguang Ren, Junjie Yue, Long Liang
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/4101745

Internet

http://dx.doi.org/10.1155/2017/4101745

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