A maximum likelihood framework for protein design

<p>Abstract</p> <p>Background</p> <p>The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, this problem can also be understood in a wider context, where additio...

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Bibliographic Details
Main Authors: Philippe Hervé, Bonnard Cécile, Rodrigue Nicolas, Kleinman Claudia L, Lartillot Nicolas
Format: Article
Language:English
Published: BMC 2006-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/7/326