Identification and Validation of Loa loa Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays
Immunoassays are currently needed to quantify Loa loa microfilariae (mf). To address this need, we have conducted proteomic and bioinformatic analyses of proteins present in the urine of a Loa mf-infected patient and used this information to identify putative biomarkers produced by L. loa mf. In tot...
Main Authors: | Papa M. Drame, Zhaojing Meng, Sasisekhar Bennuru, Jesica A. Herrick, Timothy D. Veenstra, Thomas B. Nutman |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-02-01
|
Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/7/1/e02132-15 |
Similar Items
-
Evaluation of in vitro culture systems for the maintenance of microfilariae and infective larvae of Loa loa
by: Denis Zofou, et al.
Published: (2018-05-01) -
Heterogeneity in the in vitro susceptibility of Loa loa microfilariae to drugs commonly used in parasitological infections
by: Abdel J. Njouendou, et al.
Published: (2018-04-01) -
A novel rapid test for detecting antibody responses to Loa loa infections.
by: Bijan Pedram, et al.
Published: (2017-07-01) -
Rapid molecular assays for specific detection and quantitation of Loa loa microfilaremia.
by: Doran L Fink, et al.
Published: (2011-08-01) -
Loa loa infection detection using biomarkers: current perspectives
by: Akue JP, et al.
Published: (2018-04-01)