Phthalazine-triones: Calix[4]arene-assisted synthesis using green solvents and their anticancer activities against human cancer cells

Fourteen phthalazine-triones bearing different substituents at C-4 position were synthesized through multicomponent reactions (MCR) by using phthalhydrazide, dimedone and diferent aldehydes as starting materials, p-sulfonic acid calix[4]arene as catalyst and ethyl lactate as solvent under microwave...

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Bibliographic Details
Main Authors: Yuri F. Rego, Cleiton M. da Silva, Daniel L. da Silva, Jeferson G. da Silva, Ana Lúcia T.G. Ruiz, João E. de Carvalho, Sergio A. Fernandes, Ângelo de Fátima
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535216300314