In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus

In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus

Abstract Background Since its inception in 2001, in utero electroporation (IUE) has been widely used by the neuroscience community. IUE is a technique developed to introduce plasmid DNA into embryonic mouse brains without permanently removing the embryos from the uterus. Given that IUE labels cells...

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Bibliographic Details
Main Authors: Jessica M. Rosin, Deborah M. Kurrasch
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
Hypothalamus
In utero electroporation
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12974-018-1213-6

Internet

http://link.springer.com/article/10.1186/s12974-018-1213-6

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