Biotransformation of Timosaponin BII into Seven Characteristic Metabolites by the Gut Microbiota

Biotransformation of Timosaponin BII into Seven Characteristic Metabolites by the Gut Microbiota

Timosaponin BII is one of the most abundant Anemarrhena saponins and is in a phase II clinical trial for the treatment of dementia. However, the pharmacological activity of timosaponin BII does not match its low bioavailability. In this study, we aimed to determine the effects of gut microbiota on t...

Full description

Bibliographic Details
Main Authors: Guo-Ming Dong, Hang Yu, Li-Bin Pan, Shu-Rong Ma, Hui Xu, Zheng-Wei Zhang, Pei Han, Jie Fu, Xin-Yu Yang, Adili Keranmu, Hai-Tao Niu, Jian-Dong Jiang, Yan Wang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
timosaponin BII
gut microbiota
metabolites
LC-MS/MS
LC/MS-Q-TOF
Online Access:https://www.mdpi.com/1420-3049/26/13/3861

Internet

https://www.mdpi.com/1420-3049/26/13/3861

Similar Items