Absorption and utilisation of epimedin C and icariin from Epimedii herba, and the regulatory mechanism via the BMP2/ Runx2 signalling pathway

Absorption and utilisation of epimedin C and icariin from Epimedii herba, and the regulatory mechanism via the BMP2/ Runx2 signalling pathway

Bone nonunion remains a challenge during the treatment of bone defect accompanied with infection. Epimedii herba is a widely used medicine in clinic to enhance bone healing. Epimedin C and icariin are the major flavonoid glycosides from Epimedii herba. Although the effects of these compounds have be...

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Bibliographic Details
Main Authors: Xiaowen Huang, Xuping Wang, Yang Zhang, Lifeng Shen, Nani Wang, Xuefeng Xiong, Li Zhang, Xiaobin Cai, Dan Shou
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Osteoblast
Lipopolysaccharide
Bone morphogenetic protein-2/runt-related transcription factor 2 signalling pathway
Epimedii herba
Absorption and utilisation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219325855

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http://www.sciencedirect.com/science/article/pii/S0753332219325855

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