Proteome profiling reveals novel biomarkers to identify complicated parapneumonic effusions

Abstract Patients with pneumonia and parapneumonic effusion (PPE) have elevated mortality and a poor prognosis. The aim of this study was to discover novel biomarkers to help distinguish between uncomplicated PPE (UPPE) and complicated PPE (CPPE). Using an iTRAQ-based quantitative proteomics, we ide...

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Bibliographic Details
Main Authors: Kuo-An Wu, Chih-Ching Wu, Chi-De Chen, Chi-Ming Chu, Li-Jane Shih, Yu-Ching Liu, Chih-Liang Wang, Hsi-Hsien Lin, Chia-Yu Yang
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04189-4