A Comparative Analysis of the In Vitro Anticancer Activity of Iridium(III) {η<sup>5</sup>-C<sub>5</sub>Me<sub>4</sub>R} Complexes with Variable R Groups

A Comparative Analysis of the In Vitro Anticancer Activity of Iridium(III) {η<sup>5</sup>-C<sub>5</sub>Me<sub>4</sub>R} Complexes with Variable R Groups

Piano-stool iridium complexes based on the pentamethylcyclopentadienyl ligand (Cp*) have been intensively investigated as anticancer drug candidates and hold much promise in this setting. A systematic study aimed at outlining the effect of Cp* mono-derivatization on the antiproliferative activity is...

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Bibliographic Details
Main Authors: Alice De Palo, Dijana Draca, Maria Grazia Murrali, Stefano Zacchini, Guido Pampaloni, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Fabio Marchetti
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
bioorganometallic chemistry
organoiridium complexes
cytotoxicity
apoptosis
senescence
cell proliferation
Online Access:https://www.mdpi.com/1422-0067/22/14/7422

Internet

https://www.mdpi.com/1422-0067/22/14/7422

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