Plasma mitochondrial DNA and metabolomic alterations in severe critical illness

Plasma mitochondrial DNA and metabolomic alterations in severe critical illness

Abstract Background Cell-free plasma mitochondrial DNA (mtDNA) levels are associated with endothelial dysfunction and differential outcomes in critical illness. A substantial alteration in metabolic homeostasis is commonly observed in severe critical illness. We hypothesized that metabolic profiles...

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Bibliographic Details
Main Authors: Pär I. Johansson, Kiichi Nakahira, Angela J. Rogers, Michael J. McGeachie, Rebecca M. Baron, Laura E. Fredenburgh, John Harrington, Augustine M. K. Choi, Kenneth B. Christopher
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Critical Care
Subjects:
Mitochondrial DNA
Metabolite
Metabolomics
Homeostasis
Critical illness
Acylcarnitine
Online Access:http://link.springer.com/article/10.1186/s13054-018-2275-7

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http://link.springer.com/article/10.1186/s13054-018-2275-7

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