Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells.

Dengue virus (DENV) is a re-emerging arthropod borne flavivirus that infects more than 300 million people worldwide, leading to 50,000 deaths annually. Because dendritic cells (DC) in the skin and blood are the first target cells for DENV, we sought to investigate the early molecular events involved...

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Bibliographic Details
Main Authors: David Olagnier, Suraj Peri, Courtney Steel, Nadine van Montfoort, Cindy Chiang, Vladimir Beljanski, Michael Slifker, Zhong He, Carmen N Nichols, Rongtuan Lin, Siddharth Balachandran, John Hiscott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4270780?pdf=render