Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia

<p>Abstract</p> <p>Resiniferatoxin (RTX) is an ultrapotent capsaicin analog that binds to the transient receptor potential channel, vanilloid subfamily member 1 (TRPV1). There is a large body of evidence supporting a role for TRPV1 in noxious-mediated and inflammatory hyperalgesic...

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Bibliographic Details
Main Authors: Jenkins Alan C, Zawatski Lanel, Karai Laszlo J, Mannes Andrew J, Neubert John K, Abu-Asab Mones, Iadarola Michael J
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/4/1/3