Early detection of transformation to BPDCN in a patient with MDS

Abstract Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy characterized by neoplastic cells that are positive for CD123, CD4, BDCA2, and TCL1 and aberrant expression of CD56. Historically, patients with BPDCN have an unfavorable prognosi...

Full description

Bibliographic Details
Main Authors: Kamal Chamoun, Sanam Loghavi, Naveen Pemmaraju, Marina Konopleva, Michael Kroll, Madeleine Nguyen-Cao, Marisa Hornbaker, Courtney D. DiNardo, Tapan Kadia, Jeffrey Jorgensen, Michael Andreeff, Shimin Hu, Christopher B. Benton
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Experimental Hematology & Oncology
Subjects:
MDS
Online Access:http://link.springer.com/article/10.1186/s40164-018-0117-6