The Extracellular Domains of GluN Subunits Play an Essential Role in Processing NMDA Receptors in the ER

The Extracellular Domains of GluN Subunits Play an Essential Role in Processing NMDA Receptors in the ER

N-methyl-D-aspartate receptors (NMDARs) belong to a family of ionotropic glutamate receptors that play essential roles in excitatory neurotransmission and synaptic plasticity in the mammalian central nervous system (CNS). Functional NMDARs consist of heterotetramers comprised of GluN1, GluN2A-D, and...

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Bibliographic Details
Main Authors: Martin Horak, Petra Barackova, Emily Langore, Jakub Netolicky, Paula Rivas-Ramirez, Kristyna Rehakova
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neuroscience
Subjects:
disulfide bridges
glutamate receptor
glycosylation
excitatory synapse
posttranslational modification
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.603715/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.603715/full

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