Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods
Abstract The concept that abnormal protein aggregates show prion-like propagation between cells has been considered to explain the onset and progression of many neurodegenerative diseases. Indeed, both synthetic amyloid-like fibrils and pathogenic proteins extracted from patients’ brains induce self...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-04-01
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Series: | Acta Neuropathologica Communications |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40478-018-0532-2 |