Relationship between L-DOPA-induced reduction in motor and exploratory activity and striatal dopamine D2 recptor binding in the rat

Relationship between L-DOPA-induced reduction in motor and exploratory activity and striatal dopamine D2 recptor binding in the rat

Purpose: The present study assessed the influence of L-DOPA administration on neostriatal dopamine (DA) D2 receptor binding in relation to motor and exploratory behaviors in the rat.Methods: D2 receptor binding was measured in baseline, after challenge with the aromatic L-amino acid decarboxylase in...

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Bibliographic Details
Main Authors: Susanne eNikolaus, Markus eBeu, Angelica M. De Souza Silva, Joseph P. Huston, Hubertus eHautzel, Claudia eMattern, Christina eAntke, Hans-Wilhelm eMüller
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Exploratory Behavior
habituation
motor behavior
D2 receptor
L-DOPA methylester
time-behavior curves
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00352/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00352/full

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