Long non‐coding RNA NORAD promotes the prostate cancer cell extracellular vesicle release via microRNA-541-3p-regulated PKM2 to induce bone metastasis of prostate cancer

Long non‐coding RNA NORAD promotes the prostate cancer cell extracellular vesicle release via microRNA-541-3p-regulated PKM2 to induce bone metastasis of prostate cancer

Abstract Background Bone metastasis is the leading cause of mortality and reduced quality of life in patients with metastatic prostate cancer (PCa). Long non-coding RNA activated by DNA damage (NORAD) has been observed to have an abnormal expression in various cancers. This article aimed to explore...

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Bibliographic Details
Main Authors: Chuan-yi Hu, Juan Chen, Xin-hua Qin, Pan You, Jie Ma, Jing Zhang, He Zhang, Ji-dong Xu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
NORAD
miR-541-3p
Pyruvate kinase isozymes M2
Extracellular vesicles
Prostate cancer
Bone metastasis
Online Access:https://doi.org/10.1186/s13046-021-01891-0

Internet

https://doi.org/10.1186/s13046-021-01891-0

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